Genomic evolution towards azole resistance in Candida glabrata clinical isolates unveils the importance of CgHxt4/6/7 in azole accumulation

Genomic evolution towards azole resistance in Candida glabrata clinical isolates unveils the importance of CgHxt4/6/7 in azole accumulation

Mutations in the hexose transporter, CgHXT4/6/7, contribute to increased antifungal (azole) resistance in the fungal pathogen, Candida glabrata, potentially by influencing azole accumulation.

Bibliographic Details
Main Authors: Mónica Galocha, Romeu Viana, Pedro Pais, Ana Silva-Dias, Mafalda Cavalheiro, Isabel M. Miranda, Mieke Van Ende, Caio S. Souza, Catarina Costa, Joana Branco, Cláudio M. Soares, Patrick Van Dijck, Acácio G. Rodrigues, Miguel C. Teixeira
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04087-0

Internet

https://doi.org/10.1038/s42003-022-04087-0

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