Transplantation of Adipose-Tissue-Engineered Constructs with CRISPR-Mediated UCP1 Activation

Thermogenic adipocytes have potential utility for the development of approaches to treat type 2 diabetes and obesity-associated diseases. Although several reports have proved the positive effect of beige and brown adipocyte transplantation in obese mice, translation to human cell therapy needs impro...

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Bibliographic Details
Main Authors: Svetlana Michurina, Iurii Stafeev, Maria Boldyreva, Vu Anh Truong, Elizaveta Ratner, Mikhail Menshikov, Yu-Chen Hu, Yelena Parfyonova
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/4/3844