Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein

Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein

Albumin binding domain-Derived Affinity ProTeins (ADAPTs) are small (5 kDa) engineered scaffold proteins that are promising targeting agents for radionuclide-based imaging. A recent clinical study has demonstrated that radiolabeled ADAPTs can efficiently visualize human epidermal growth factor recep...

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Bibliographic Details
Main Authors: Anzhelika Vorobyeva, Maryam Oroujeni, Sarah Lindbo, Sophia Hober, Tianqi Xu, Yongsheng Liu, Sara S. Rinne, Javad Garousi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
kidney
reabsorption
renal uptake
radionuclide
ADAPT
Online Access:https://www.mdpi.com/1420-3049/25/19/4448

Internet

https://www.mdpi.com/1420-3049/25/19/4448

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