Road testing new CAR design strategies in multiple myeloma

Road testing new CAR design strategies in multiple myeloma

A deeper understanding of basic immunology principles and advances in bioengineering have accelerated the mass production of genetically-reprogrammed T-cells as living drugs to treat human diseases. Autologous and allogeneic cytotoxic T-cells have been weaponized to brandish MHC-independent chimeric...

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Bibliographic Details
Main Authors: Priyanka S. Rana, Elena V. Murphy, Jeries Kort, James J. Driscoll
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
CAR T-cell therapy
multiple myeloma
hypoxia
armored CAR
self-driving CAR
logic-gates
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.957157/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.957157/full

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