Dose Selection in Preclinical Studies: Cross-Species Dose Conversion

One of the major obstacles to effective translational medicine is the challenge of translating animal research results into clinical studies. Scientific literature mainly addresses the selection of the drug dose at initiation of clinical trials (Phase 1). Appropriate selection of doses is also essen...

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Bibliographic Details
Main Authors: E. V. Shekunova, M. A. Kovaleva, M. N. Makarova, V. G. Makarov
Format: Article
Language:Russian
Published: NEICON ISP LLC 2020-02-01
Series:Ведомости Научного центра экспертизы средств медицинского применения
Subjects:
Online Access:https://www.vedomostincesmp.ru/jour/article/view/279