Empagliflozin restores cardiac metabolic flexibility in diet-induced obese C57BL6/J mice

Empagliflozin restores cardiac metabolic flexibility in diet-induced obese C57BL6/J mice

Sodium-glucose co-transporter type 2 (SGLT2) inhibitor therapy to treat type 2 diabetes unexpectedly reduced all-cause mortality and hospitalization due to heart failure in several large-scale clinical trials, and has since been shown to produce similar cardiovascular disease-protective effects in p...

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Bibliographic Details
Main Authors: Bingxian Xie, Wesley Ramirez, Amanda M. Mills, Brydie R. Huckestein, Moira Anderson, Martha M. Pangburn, Eric Y. Lang, Steven J. Mullet, Byron W. Chuan, Lanping Guo, Ian Sipula, Christopher P. O'Donnell, Stacy G. Wendell, Iain Scott, Michael J. Jurczak
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Physiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2665944122000220

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http://www.sciencedirect.com/science/article/pii/S2665944122000220

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