Multiplexed immunofluorescence analysis of CAF-markers, EZH2 and FOXM1 in gastric tissue: associations with clinicopathological parameters and clinical outcomes

Multiplexed immunofluorescence analysis of CAF-markers, EZH2 and FOXM1 in gastric tissue: associations with clinicopathological parameters and clinical outcomes

Abstract Background The aim of this study is to explore the expression and clinical relevance of CAF-associated markers, EZH2 and FOXM1 in gastric samples. Methods Protein expression were detected and evaluated by multi-plex immunofluorescence (mIF) in 93 cases of gastric cancer (GC) and 31 cases of...

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Bibliographic Details
Main Authors: Hui Sun, Xin Wang, Xiaoyan Zhang, Xu Wang, Cong Tan, Weiwei Weng, Meng Zhang, Shujuan Ni, Lei Wang, Dan Huang, Midie Xu, Weiqi Sheng
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Cancer
Subjects:
EZH2
FOXM1
Cancer associated fibroblast
FAP
Prognosis
Gastric cancer
Online Access:https://doi.org/10.1186/s12885-022-10312-0

Internet

https://doi.org/10.1186/s12885-022-10312-0

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