Platelets activated by the anti-β2GPI/β2GPI complex release microRNAs to inhibit migration and tube formation of human umbilical vein endothelial cells

Platelets activated by the anti-β2GPI/β2GPI complex release microRNAs to inhibit migration and tube formation of human umbilical vein endothelial cells

Abstract Background Patients with anti-β2GPI antibodies display significantly higher platelet activation/aggregation and vascular endothelial cell damage. The mechanism underlying the correlation between platelet activation, vascular endothelial cell dysfunctions and anti-β2GPI antibodies remains un...

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Bibliographic Details
Main Authors: Yanfen Zhang, Wenjing Zhang, Caijun Zha, Yanhong Liu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
Platelet-derived microparticles
MicroRNA
Endothelial cells
Online Access:http://link.springer.com/article/10.1186/s11658-018-0091-3

Internet

http://link.springer.com/article/10.1186/s11658-018-0091-3

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