The skin hydration and anti-inflammatory potential of zerumbone, a natural sesquiterpene of Zingiber zerumbet, enhanced Src/ERK-mediated HAS-2/AQP-3 and inhibited NFκB/AP-1 expression in UVB-irradiated human keratinocytes

The skin hydration and anti-inflammatory potential of zerumbone, a natural sesquiterpene of Zingiber zerumbet, enhanced Src/ERK-mediated HAS-2/AQP-3 and inhibited NFκB/AP-1 expression in UVB-irradiated human keratinocytes

We assayed skin hydration and anti-inflammatory efficacies of zerumbone (Zer, 2.5–10 μM), a natural sesquiterpene of Zingiber zerumbet, using non– or UVB (30 mJ/cm2)-irradiated keratinocytes (HaCaT). & Zer increased cell viability, upregulated hyaluronic acid, and inhibited ROS generation in...

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Bibliographic Details
Main Authors: Hsin-Ling Yang, Siang-Jyun Chen, Sudhir Pandey, I-Chen Wu, Yi-Ting Chung, Chithravel Vadivalagan, Jhih-Hsuan Hseu, You-Cheng Hseu
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Functional Foods
Subjects:
Zingiber zerumbet
Zerumbone
UVB
Nrf2
Skin hydration
Anti-inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623004905

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http://www.sciencedirect.com/science/article/pii/S1756464623004905

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