Efficient genome editing in Claviceps purpurea using a CRISPR/Cas9 ribonucleoprotein method
Claviceps purpurea produces many pharmacologically important ergot alkaloids (EAS), which are widely used to treat migraine and hypertension and to aid childbirth. Although an EAS biosynthetic cluster of C. purpurea has been discovered more than 20 years ago, the complete biosynthetic pathway of EAS...
| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado: |
KeAi Communications Co., Ltd.
2022-06-01
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| Series: | Synthetic and Systems Biotechnology |
| Subjects: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2405805X22000096 |