Bladder cancer-derived exosomal KRT6B promotes invasion and metastasis by inducing EMT and regulating the immune microenvironment

Bladder cancer-derived exosomal KRT6B promotes invasion and metastasis by inducing EMT and regulating the immune microenvironment

Abstract Background Tumour-derived exosomes have recently been shown to participate in the formation and progression of different cancer processes, including tumour microenvironment remodelling, angiogenesis, invasion, metastasis, and drug resistance. However, the function and mechanism of exosome-e...

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Bibliographic Details
Main Authors: Qiang Song, Hao Yu, Yidong Cheng, Jie Han, Kai Li, Juntao Zhuang, Qiang Lv, Xiao Yang, Haiwei Yang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Translational Medicine
Subjects:
Bladder cancer
Exosome
krt6b
Epithelial–mesenchymal transition
Immune response
Prognosis marker
Online Access:https://doi.org/10.1186/s12967-022-03508-2

Internet

https://doi.org/10.1186/s12967-022-03508-2

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