Building synthetic chromosomes from natural DNA

Abstract De novo chromosome synthesis is costly and time-consuming, limiting its use in research and biotechnology. Building synthetic chromosomes from natural components is an unexplored alternative with many potential applications. In this paper, we report CReATiNG (Cloning, Reprogramming, and Ass...

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Bibliographic Details
Main Authors: Alessandro L. V. Coradini, Christopher Ne Ville, Zachary A. Krieger, Joshua Roemer, Cara Hull, Shawn Yang, Daniel T. Lusk, Ian M. Ehrenreich
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44112-2