Tourniquet use following blast-associated complex lower limb injury and traumatic amputation promotes end organ dysfunction and amplified heterotopic ossification formation

Tourniquet use following blast-associated complex lower limb injury and traumatic amputation promotes end organ dysfunction and amplified heterotopic ossification formation

Abstract Background Traumatic heterotopic ossification (tHO) is characterized by ectopic bone formation in extra-skeletal sites leading to impaired wound healing, entrapment of neurovascular structures, pain, and reduced range of motion. HO has become a signature pathology affecting wounded military...

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Bibliographic Details
Main Authors: Philip J. Spreadborough, Amy L. Strong, John Mares, Benjamin Levi, Thomas A. Davis
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Tourniquets
Blast injury
Traumatic heterotopic ossification
Complex limb injury
Ischemia reperfusion
Online Access:https://doi.org/10.1186/s13018-022-03321-z

Internet

https://doi.org/10.1186/s13018-022-03321-z

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