Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells.

The aims of this study are to demonstrate the increased lysis of stem cells but not their differentiated counterparts by the NK cells and to determine whether disturbance in cell differentiation is a cause for increased sensitivity to NK cell mediated cytotoxicity. Increased cytotoxicity and augment...

Full description

Bibliographic Details
Main Authors: Han-Ching Tseng, Aida Arasteh, Avina Paranjpe, Antonia Teruel, Wendy Yang, Armin Behel, Jackelyn A Alva, Gina Walter, Christian Head, Tomo-o Ishikawa, Harvey R Herschman, Nicholas Cacalano, April D Pyle, No-Hee Park, Anahid Jewett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2905395?pdf=render