Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells.
The aims of this study are to demonstrate the increased lysis of stem cells but not their differentiated counterparts by the NK cells and to determine whether disturbance in cell differentiation is a cause for increased sensitivity to NK cell mediated cytotoxicity. Increased cytotoxicity and augment...
Main Authors: | Han-Ching Tseng, Aida Arasteh, Avina Paranjpe, Antonia Teruel, Wendy Yang, Armin Behel, Jackelyn A Alva, Gina Walter, Christian Head, Tomo-o Ishikawa, Harvey R Herschman, Nicholas Cacalano, April D Pyle, No-Hee Park, Anahid Jewett |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2905395?pdf=render |
Similar Items
-
Strategies to rescue mesenchymal stem cells (MSCs) and dental pulp stem cells (DPSCs) from NK cell mediated cytotoxicity.
by: Anahid Jewett, et al.
Published: (2010-01-01) -
Induction of split anergy conditions Natural Killer cells to promote differentiation of stem cells through cell-cell contact and secreted factors
by: Han-Ching eTseng, et al.
Published: (2014-06-01) -
Tumor Induced Inactivation of Natural Killer Cell Cytotoxic Function; Implication in Growth, Expansion and Differentiation of Cancer Stem Cells
by: Anahid Jewett, Han-Ching Tseng
Published: (2011-01-01) -
The Potential Effect of Novel Coronavirus SARS-CoV-2 on NK Cells; A Perspective on Potential Therapeutic Interventions
by: Anahid Jewett, et al.
Published: (2020-07-01) -
Probiotic-Treated Super-Charged NK Cells Efficiently Clear Poorly Differentiated Pancreatic Tumors in Hu-BLT Mice
by: Kawaljit Kaur, et al.
Published: (2019-12-01)