New and simplified method for drug combination studies by checkerboard assay

To evaluate the effect of two combined antimicrobial drugs, one method currently in use is the checkerboard assay in a 96-well microplate, which gives a good in vivo estimation of the drug-drug combination effect. Appropriate and consolidated methods are described in numerous scientific publications...

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Bibliographic Details
Main Authors: Pierangelo Bellio, Lorenza Fagnani, Lisaurora Nazzicone, Giuseppe Celenza
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016121003356