PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression

PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression

Abstract Phosphatidylinositol glycan anchor biosynthesis class N (PIGN) has been linked to the suppression of chromosomal instability. The spindle assembly checkpoint complex is responsible for proper chromosome segregation during mitosis to prevent chromosomal instability. In this study, the novel...

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Bibliographic Details
Main Authors: Emmanuel K. Teye, Shasha Lu, Fangyuan Chen, Wenrui Yang, Thomas Abraham, Douglas B. Stairs, Hong-Gang Wang, Gregory S. Yochum, Robert A. Brodsky, Jeffrey J. Pu
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98218-y

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https://doi.org/10.1038/s41598-021-98218-y

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