ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)

ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)

Cell death is central to development, organismal homeostasis, and immune responses. The cell death field has experienced tremendous progress by delineating the molecular programs specific to each of the apoptotic and inflammatory cell death pathways. Moreover, the discovery of the inflammasomes and...

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Bibliographic Details
Main Authors: R. K. Subbarao Malireddi, Sannula Kesavardhana, Thirumala-Devi Kanneganti
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
caspase-1
gasdermin D
MLKL
inflammasome
infection
innate immunity
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00406/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00406/full

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