Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface

The septin family of eukaryotic proteins comprises distinct classes of sequence-related monomers that associate in a defined order into linear hetero-oligomers, which are capable of polymerizing into cytoskeletal filaments. Like actin and ⍺ and β tubulin, most septin monomers require binding of a nu...

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Bibliographic Details
Main Authors: Alya Hussain, Vu T. Nguyen, Philip Reigan, Michael McMurray
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1296657/full