Cytoglobin regulates NO-dependent cilia motility and organ laterality during development

Abstract Cytoglobin is a heme protein with unresolved physiological function. Genetic deletion of zebrafish cytoglobin (cygb2) causes developmental defects in left-right cardiac determination, which in humans is associated with defects in ciliary function and low airway epithelial nitric oxide produ...

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Bibliographic Details
Main Authors: Elizabeth R. Rochon, Jianmin Xue, Manush Sayd Mohammed, Caroline Smith, Anders Hay-Schmidt, Anthony W. DeMartino, Adam Clark, Qinzi Xu, Cecilia W. Lo, Michael Tsang, Jesus Tejero, Mark T. Gladwin, Paola Corti
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43544-0