Defects of renal tubular homeostasis and cystogenesis in the Pkhd1 knockout

Defects of renal tubular homeostasis and cystogenesis in the Pkhd1 knockout

Summary: Loss of PKHD1-gene function causes autosomal recessive polycystic kidney disease (ARPKD) characterized by bilateral severely enlarged kidneys and congenital liver fibrosis requiring kidney replacement therapy most frequently during childhood. Studies using renal tissue from ARPKD patients s...

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Bibliographic Details
Main Authors: Julia C. Fox, Susanne T. Hahnenstein, Fatima Hassan, Andrea Grund, Dieter Haffner, Wolfgang H. Ziegler
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Nephrology
Physiology
Molecular biology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224007089

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http://www.sciencedirect.com/science/article/pii/S2589004224007089

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