The interplay between autophagy and ROS in tumorigenesis

Reactive oxygen species (ROS) at physiological levels are important cell signaling molecules. However, aberrantly high ROS are intimately associated with disease and commonly observed in cancer. Mitochondria are primary sources of intracellular ROS, and their maintenance is essential to cellular h...

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Bibliographic Details
Main Authors: Sameera eKongara, Vassiliki eKarantza
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00171/full