Raman microspectroscopy fingerprinting of organoid differentiation state

Highlights Salivary gland organoids have unique Raman signatures detectable with a confocal-based Raman imaging approach. Raman signatures can be detected in unlabeled fixed or live organoids. Raman spectral signatures effectively predict organoid phenotypes.

Bibliographic Details
Main Authors: Kate Tubbesing, Nicholas Moskwa, Ting Chean Khoo, Deirdre A. Nelson, Anna Sharikova, Yunlong Feng, Melinda Larsen, Alexander Khmaladze
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-022-00347-3