Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System

Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System

Objective: Human adipose-derived mesenchymal stromal/stem cells (hASC) constitute an attractive source of stemcells for cell-based therapies in regenerative medicine and tissue engineering as they are easy to acquire fromlipoaspirate, expansion, and genetic modification ex vivo. The combination of P...

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Bibliographic Details
Main Authors: Hiroyuki Moriyama, Mariko Moriyama, Toshiyuki Ozawa, Daisuke Tsuruta, Takao Hayakawa
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2022-12-01
Series:Cell Journal
Subjects:
adipose-derived mesenchymal stromal/stem cells
doxycycline
insulin-producing cells
gene expression regulation
genetic vectors
Online Access:https://www.celljournal.org/article_254113_d41d8cd98f00b204e9800998ecf8427e.pdf

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https://www.celljournal.org/article_254113_d41d8cd98f00b204e9800998ecf8427e.pdf

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