The NP protein of Newcastle disease virus dictates its oncolytic activity by regulating viral mRNA translation efficiency.

Newcastle disease virus (NDV) has been extensively studied as a promising oncolytic virus for killing tumor cells in vitro and in vivo in clinical trials. However, the viral components that regulate the oncolytic activity of NDV remain incompletely understood. In this study, we systematically compar...

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Bibliographic Details
Main Authors: Tianxing Liao, Yu Chen, Lili Guo, Shanshan Zhu, Tiansong Zhan, Xiaolong Lu, Haixu Xu, Zenglei Hu, Jiao Hu, Min Gu, Xiaowen Liu, Xiaoquan Wang, Shunlin Hu, Xiufan Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012027