Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation

Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation

Activation of mitophagy was considered to be a potential therapeutic strategy for intervertebral disc degeneration (IDD). There was evidence suggesting that hyaluronic acid (HA) can protect mitochondria from oxidative stress in chondrocytes, but its protective effects and mechanism in nucleus pulpos...

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Bibliographic Details
Main Authors: Fu Zhang, Songjuan Wang, Manman Gao, Baoliang Li, Zhongyuan He, Tao Tang, Zhengya Zhu, Shaoyu Liu, Zhiyu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
intervertebral disc degeneration
hyaluronic acid
mitophagy
oxidative stress
C1QBP
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1057429/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1057429/full

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