microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection.

Mechanisms of hepatic carcinogenesis in chronic hepatitis B and hepatitis C are incompletely defined but often assumed to be similar and related to immune-mediated inflammation. Despite this, several studies hint at differences in expression of miR-122, a liver-specific microRNA with tumor suppresso...

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Bibliographic Details
Main Authors: Carolyn Spaniel, Masao Honda, Sara R Selitsky, Daisuke Yamane, Tetsuro Shimakami, Shuichi Kaneko, Robert E Lanford, Stanley M Lemon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3793926?pdf=render