Canonical BMP Signaling Executes Epithelial-Mesenchymal Transition Downstream of SNAIL1

Canonical BMP Signaling Executes Epithelial-Mesenchymal Transition Downstream of SNAIL1

Epithelial-mesenchymal transition (EMT) is a pivotal process in development and disease. In carcinogenesis, various signaling pathways are known to trigger EMT by inducing the expression of EMT transcription factors (EMT-TFs) like SNAIL1, ultimately promoting invasion, metastasis and chemoresistance...

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Bibliographic Details
Main Authors: Patrick Frey, Antoine Devisme, Monika Schrempp, Geoffroy Andrieux, Melanie Boerries, Andreas Hecht
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
Epithelial-mesenchymal transition (EMT)
SNAIL1
BMP signaling
SMAD
colorectal cancer
pancreatic cancer
Online Access:https://www.mdpi.com/2072-6694/12/4/1019

Internet

https://www.mdpi.com/2072-6694/12/4/1019

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