Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses

Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has decreased the efficacy of SARS-CoV-2 vaccines in containing coronavirus disease 2019 (COVID-19) over time, and booster vaccination strategies are urgently necessitated to achieve sufficient protection. Intrana...

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Bibliographic Details
Main Authors: Li Chen, Wenyan Ren, Hong Lei, Jiayu Wang, Haiying Que, Dandan Wan, Aqu Alu, Dandan Peng, Minyang Fu, Weiqi Hong, Yuhe Huang, Xiangrong Song, Guangwen Lu, Xiawei Wei
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-07-01
Series:Genes and Diseases
Subjects:
Heterologous immunization
Intranasal immunization
mRNA vaccine
SARS-CoV-2
Subunit protein vaccine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223003483

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http://www.sciencedirect.com/science/article/pii/S2352304223003483

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