SCAMP5 mediates activity-dependent enhancement of NHE6 recruitment to synaptic vesicles during synaptic plasticity

Abstract Na+(K+)/H+ exchanger 6 (NHE6) on synaptic vesicle (SV) is critical for the presynaptic regulation of quantal size at the glutamatergic synapses by converting the chemical gradient (ΔpH) into membrane potential (Δψ) across the SV membrane. We recently found that NHE6 directly interacts with...

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Bibliographic Details
Main Authors: Unghwi Lee, Seung Hyun Ryu, Sunghoe Chang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-021-00763-0