VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion

Summary: Extracellular vesicles (EVs) participate in intercellular communication and contribute to the angiogenesis. However, the understanding of the mechanisms underlying EVs secretion by neurons and their action on the vascular system of the central nervous system (CNS) remain rudimentary. Here,...

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Bibliographic Details
Main Authors: Xiaohua Dong, Dongya Jiang, Long Wang, Jing Zhao, Lingling Yu, Yun Huang, Xiaohui Wu, Yanqing Zhu, Yingmin Zhao, Qingshun Zhao, Guangming Zhang, Xinyuan Li
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222003121