Morphine-Induced Analgesic Tolerance Effect on Gene Expression of the NMDA Receptor Subunit 1 in Rat Striatum and Prefrontal Cortex

Introduction: Morphine is a potent analgesic but its continual use results in analgesic tolerance. Mechanisms of this tolerance remain to be clarified. However, changes in the functions of μ-opioid and N-Methyl-D-aspartate (NMDA) receptors have been proposed in morphine&...

Full description

Bibliographic Details
Main Authors: Shamseddin Ahmadi, Fatemeh Rafieenia, Jalal Rostamzadeh
Format: Article
Language:English
Published: Iran University of Medical Sciences 2016-07-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-373-3&slc_lang=en&sid=1