Immunoglobulin-like transcript 2 as an impaired anti-tumor cytotoxicity marker of natural killer cells in patients with hepatocellular carcinoma

Immunoglobulin-like transcript 2 as an impaired anti-tumor cytotoxicity marker of natural killer cells in patients with hepatocellular carcinoma

IntroductionNatural killer (NK) cells play a pivotal role in immune surveillance in the liver. We aimed to identify potential targets for NK cell-mediated immune intervention by revealing the functional molecules on NK cells in HCC patients.MethodsTo evaluate the impact of aging on NK cell phenotype...

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Bibliographic Details
Main Authors: Toshihiro Sakata, Sachiyo Yoshio, Taiji Yamazoe, Taizo Mori, Eiji Kakazu, Yoshihiko Aoki, Nobuyoshi Aoyanagi, Toru Okamoto, Takanori Ito, Hidenori Toyoda, Takumi Kawaguchi, Yoshihiro Ono, Yu Takahashi, Akinobu Taketomi, Tatsuya Kanto
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
NK cells
ILT2
HLA-G
HCC
MIF
ADCC
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1389411/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1389411/full

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