Identification of clinically relevant subsets CD39+PD-1+CD8+ T cells and CD39+ regulatory T cells in intrahepatic cholangiocarcinoma using single-cell CyTOF

Identification of clinically relevant subsets CD39+PD-1+CD8+ T cells and CD39+ regulatory T cells in intrahepatic cholangiocarcinoma using single-cell CyTOF

Intrahepatic cholangiocarcinoma (iCCA) is an aggressive liver malignancy with limited treatment options and a dismal prognosis. The tumor immune microenvironment (TIME) is crucial for iCCA progression, yet its comprehensive characterization remains incomplete. This study utilized mass cytometry by t...

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Bibliographic Details
Main Authors: Qi-Wei Zhang, Meng-Xuan Zhu, Wen-Feng Liu, Wei-Wei Rui, Yong Chen, Xiao-Yi Ding, Yong-Sheng Jiang, Zhi-Yuan Wu, Bin-Bin Liu
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Translational Oncology
Subjects:
Mass cytometry
Single cell analysis
Intrahepatic cholangiocarcinoma
Immune microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000810

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http://www.sciencedirect.com/science/article/pii/S1936523324000810

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