Maternal Metformin Treatment during Gestation and Lactation Improves Skeletal Muscle Development in Offspring of Rat Dams Fed High-Fat Diet

Maternal Metformin Treatment during Gestation and Lactation Improves Skeletal Muscle Development in Offspring of Rat Dams Fed High-Fat Diet

Maternal high-fat (HF) diet is associated with offspring metabolic disorder. This study intended to determine whether maternal metformin (MT) administration during gestation and lactation prevents the effect of maternal HF diet on offspring’s skeletal muscle (SM) development and metabolism. Pregnant...

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Bibliographic Details
Main Authors: Jiaqi Cui, Lin Song, Rui Wang, Shuyuan Hu, Zhao Yang, Zengtie Zhang, Bo Sun, Wei Cui
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Nutrients
Subjects:
maternal diet
metformin
skeletal muscle
mitochondria
AMPK
mTOR
Online Access:https://www.mdpi.com/2072-6643/13/10/3417

Internet

https://www.mdpi.com/2072-6643/13/10/3417

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