Clinical application of the HM-1000 image processing for HER2 fluorescence in situ hybridization signal quantification in breast cancer

Abstract Background Accurate quantification of human epidermal growth factor receptor 2 (HER2) gene amplification is important for predicting treatment response and prognosis in patients with breast cancer. Fluorescence in situ hybridization (FISH) is the gold standard for the diagnosis of HER2 stat...

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Bibliographic Details
Main Authors: Vicente Peg, Teresa Moline, Miquel Roig, Yuko Saruta, Santiago Ramon y Cajal
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Diagnostic Pathology
Subjects:
Online Access:https://doi.org/10.1186/s13000-024-01455-8