Genetic Polymorphisms of the Telomerase Reverse Transcriptase Gene in Relation to Prostate Tumorigenesis, Aggressiveness and Mortality: A Cross-Ancestry Analysis

Genetic Polymorphisms of the Telomerase Reverse Transcriptase Gene in Relation to Prostate Tumorigenesis, Aggressiveness and Mortality: A Cross-Ancestry Analysis

Background: Telomerase reverse transcriptase (<i>TERT</i>) has been consistently associated with prostate cancer (PCa) risk. However, few studies have explored the association between <i>TERT</i> variants and PCa aggressiveness. Methods: Individual and genetic data were obtai...

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Bibliographic Details
Main Authors: Yongle Zhan, Xiaohao Ruan, Jiacheng Liu, Da Huang, Jingyi Huang, Jinlun Huang, Tsun Tsun Stacia Chun, Ada Tsui-Lin Ng, Yishuo Wu, Gonghong Wei, Haowen Jiang, Danfeng Xu, Rong Na
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cancers
Subjects:
prostate cancer
aggressive prostate cancer
prostate cancer death
telomerase reverse transcriptase
single nucleotide polymorphism
cross-ancestry
Online Access:https://www.mdpi.com/2072-6694/15/9/2650

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https://www.mdpi.com/2072-6694/15/9/2650

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