Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress

Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress

Our previous research indicates that the extracellular signal-regulated kinase (ERK)-cyclic AMP-responsive-element-binding protein (CREB) signal system may be involved in the molecular mechanism of depression. The present study further investigated the effect of antidepressant fluoxetine on the ERK-...

Full description

Bibliographic Details
Main Authors: Xiaoli Qi, Wenjuan Lin, Junfa Li, Huanhuan Li, Weiwen Wang, Donglin Wang, Meng Sun
Format: Article
Language:English
Published: Elsevier 2008-08-01
Series:Neurobiology of Disease
Subjects:
ERK
CREB
Stress
Antidepressant
Hippocampus
Prefrontal cortex
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000971

Internet

http://www.sciencedirect.com/science/article/pii/S0969996108000971

Similar Items