Ageing-Induced Decline in Primary Myeloid Cell Phagocytosis Is Unaffected by Optineurin Insufficiency

Ageing-Induced Decline in Primary Myeloid Cell Phagocytosis Is Unaffected by Optineurin Insufficiency

Optineurin is a ubiquitin-binding adaptor protein involved in multiple cellular processes, including innate inflammatory signalling. Mutations in optineurin were found in amyotrophic lateral sclerosis, an adult-onset fatal neurodegenerative disease that targets motor neurons. Neurodegeneration resul...

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Autors principals: Josip Peradinovic, Nikolina Mohovic, Katarina Bulic, Andrea Markovinovic, Raffaello Cimbro, Ivana Munitic
Format: Article
Idioma:English
Publicat: MDPI AG 2023-02-01
Col·lecció:Biology
Matèries:
phagocytosis
ageing
optineurin
neurodegeneration
inflammation
Accés en línia:https://www.mdpi.com/2079-7737/12/2/240

Internet

https://www.mdpi.com/2079-7737/12/2/240

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