Fibrotic Scar After Spinal Cord Injury: Crosstalk With Other Cells, Cellular Origin, Function, and Mechanism

Fibrotic Scar After Spinal Cord Injury: Crosstalk With Other Cells, Cellular Origin, Function, and Mechanism

The failure of axonal regeneration after spinal cord injury (SCI) results in permanent loss of sensorimotor function. The persistent presence of scar tissue, mainly fibrotic scar and astrocytic scar, is a critical cause of axonal regeneration failure and is widely accepted as a treatment target for...

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Bibliographic Details
Main Authors: Ziyu Li, Shuisheng Yu, Xuyang Hu, Yiteng Li, Xingyu You, Dasheng Tian, Li Cheng, Meige Zheng, Juehua Jing
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
spinal cord injury
fibrotic scar
crosstalk
cellular origin
treatment strategy
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.720938/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.720938/full

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