Development of [18F]-PSS223 as a PET Tracer for Imaging of Metabotropic Glutamate Receptor Subtype 5 (mGluR5)
Involvement of metabotropic glutamate receptor subtype 5 (mGluR5) in physiological and pathophysiological processes in the brain has been demonstrated, and hence mGluR5 has emerged as an important drug target. [11C]-ABP688 is clinically the most successful mGluR5 positron emission tomograp...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | deu |
Published: |
Swiss Chemical Society
2012-04-01
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Series: | CHIMIA |
Subjects: | |
Online Access: | https://www.chimia.ch/chimia/article/view/5189 |