Development of [18F]-PSS223 as a PET Tracer for Imaging of Metabotropic Glutamate Receptor Subtype 5 (mGluR5)

Involvement of metabotropic glutamate receptor subtype 5 (mGluR5) in physiological and pathophysiological processes in the brain has been demonstrated, and hence mGluR5 has emerged as an important drug target. [11C]-ABP688 is clinically the most successful mGluR5 positron emission tomograp...

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Bibliographic Details
Main Authors: Selena Milicevic Sephton, Patrick Dennler, Dominique S. Leutwiler, Linjing Mu, Roger Schibli, Stefanie D. Krämer, Simon M. Ametamey
Format: Article
Language:deu
Published: Swiss Chemical Society 2012-04-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/5189