Quantification of surface-localized and total oxytocin receptor in myometrial smooth muscle cells

Oxytocin acts through the oxytocin receptor (OXTR) to modulate uterine contractility. We previously identified OXTR genetic variants and showed that, in HEK293T cells, two of the OXTR protein variants localized to the cell surface less than wild-type OXTR. Here, we sought to measure OXTR in the more...

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Bibliographic Details
Main Authors: Yingye Fang, Erin L. Reinl, Audrey Liu, Trinidi D. Prochaska, Manasi Malik, Antonina I. Frolova, Sarah K. England, Princess I. Imoukhuede
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024017924