A local and global sensitivity analysis of a mathematical model of coagulation and platelet deposition under flow.

The hemostatic response involves blood coagulation and platelet aggregation to stop blood loss from an injured blood vessel. The complexity of these processes make it difficult to intuit the overall hemostatic response without quantitative methods. Mathematical models aim to address this challenge b...

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Bibliographic Details
Main Authors: Kathryn G Link, Michael T Stobb, Jorge Di Paola, Keith B Neeves, Aaron L Fogelson, Suzanne S Sindi, Karin Leiderman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200917&type=printable