Fine particulate matter aggravates smoking induced lung injury via NLRP3/caspase-1 pathway in COPD

Fine particulate matter aggravates smoking induced lung injury via NLRP3/caspase-1 pathway in COPD

Abstract Background Exposure to noxious particles, including cigarette smoke and fine particulate matter (PM2.5), is a risk factor for chronic obstructive pulmonary disease (COPD) and promotes inflammation and cell death in the lungs. We investigated the combined effects of cigarette smoking and PM2...

Full description

Bibliographic Details
Main Authors: Chiwook Chung, Suk Young Park, Jin-Young Huh, Na Hyun Kim, ChangHo Shon, Eun Yi Oh, Young-Jun Park, Seon-Jin Lee, Hwan-Cheol Kim, Sei Won Lee
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Inflammation
Subjects:
PM2.5
Smoking
Pyroptosis
NLRP3
COPD
Online Access:https://doi.org/10.1186/s12950-024-00384-z

Internet

https://doi.org/10.1186/s12950-024-00384-z

Similar Items