Prognostic significance of ESR1 gene amplification, mRNA/protein expression and functional profiles in high-risk early breast cancer: a translational study of the Hellenic Cooperative Oncology Group (HeCOG).

<h4>Background</h4>Discrepant data have been published on the incidence and prognostic significance of ESR1 gene amplification in early breast cancer.<h4>Patients and methods</h4>Formalin-fixed paraffin-embedded tumor blocks were collected from women with early breast cancer...

Full description

Bibliographic Details
Main Authors: George Pentheroudakis, Vassiliki Kotoula, Anastasia G Eleftheraki, Eleftheria Tsolaki, Ralph M Wirtz, Konstantine T Kalogeras, Anna Batistatou, Mattheos Bobos, Meletios A Dimopoulos, Eleni Timotheadou, Helen Gogas, Christos Christodoulou, Kyriaki Papadopoulou, Ioannis Efstratiou, Chrisoula D Scopa, Irene Papaspyrou, Dimitrios Vlachodimitropoulos, Helena Linardou, Epaminontas Samantas, Dimitrios Pectasides, Nicholas Pavlidis, George Fountzilas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23923010/pdf/?tool=EBI