Computational exploration of Picrasma quassioides compounds as CviR-mediated quorum sensing inhibitors against Chromobacterium violaceum

Computational exploration of Picrasma quassioides compounds as CviR-mediated quorum sensing inhibitors against Chromobacterium violaceum

Chromobacterium violaceum an opportunistic human pathogenic bacterium, exhibits resistance to conventional antibiotics by exploiting its quorum sensing mechanism to regulate virulence factor expression. In light of this, disrupting the quorum sensing mechanism presents a promising avenue for treatin...

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Bibliographic Details
Main Authors: Prasanna D. Revanasiddappa, Gowtham H. G., Chandana K. P., Shilpa Natarajamurthy, Nataraj K., Sushma Pradeep, Chandan Shivamallu, Gehan M. Elossaily, Raghu Ram Achar, Ekaterina Silina, Victor Stupin, Natalia Manturova, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Amruthesh Kestur Nagaraj, Murali Mahadevamurthy, Shiva Prasad Kollur
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Chemistry
Subjects:
Chromobacterium violaceum
CviR protein
in silico
Picrasma quassioides
quorum sensing
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2024.1286675/full

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https://www.frontiersin.org/articles/10.3389/fchem.2024.1286675/full

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