p16INK4a and γ-H2AX as Biomarkers of Senescence in Skin Tissue: A Cadaveric Cross-sectional Study at a Tertiary Care Centre in Punjab, India

Introduction: Baseline expression of p16INK4a characterises cellular senescence. Similarly, the measurement of γ-GammaH2AX (γ-H2AX) foci levels in cells provides a reliable method for quantification of Deoxyribonucleic Acid (DNA) damage. Aim: To explore the role of p16INK4a and γ-H2AX as biomarke...

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Bibliographic Details
Main Authors: Richa Gupta, Anjali Aggarwal, Tulika Gupta, Chiman Kumari
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2023-10-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/18613/64549_CE[Ra1]_F(IS)_QC(KK_RDW_IS)_PF1(RI_KM_OM)_PFA(KM)