TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer

TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer

Abstract Background Prostate adenocarcinoma (PRAD) is the second leading cause of cancer-related deaths in men. High variability in DNA methylation and a high rate of large genomic rearrangements are often observed in PRAD. Results To investigate the reasons for such high variance, we integrated DNA...

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Bibliographic Details
Main Authors: R. Sultanov, A. Mulyukina, O. Zubkova, A. Fedoseeva, A. Bogomazova, K. Klimina, A. Larin, T. Zatsepin, T. Prikazchikova, M. Lukina, M. Bogomiakova, E. Sharova, E. Generozov, M. Lagarkova, G. Arapidi
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Epigenetics & Chromatin
Subjects:
TP63
TRIM29
Epigenetic regulation
Prostate cancer
WGCNA
Online Access:https://doi.org/10.1186/s13072-024-00529-7

Internet

https://doi.org/10.1186/s13072-024-00529-7

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