TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior

TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior

Abstract Recent studies have suggested that the use of cognitive enhancers as adjuncts to exposure-based therapy in individuals suffering from post-traumatic stress disorder (PTSD) may be beneficial. Brain cholinergic signaling through basal forebrain projections to the hippocampus is an established...

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Bibliographic Details
Main Authors: Sudhirkumar Yanpallewar, Francesco Tomassoni-Ardori, Mary Ellen Palko, Zhenyi Hong, Erkan Kiris, Jodi Becker, Gianluca Fulgenzi, Lino Tessarollo
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01869-2

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https://doi.org/10.1038/s41398-022-01869-2

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