Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity

Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity

IMPORTANCE:. Vascular dysfunction and capillary leak are common in critically ill COVID-19 patients, but identification of endothelial pathways involved in COVID-19 pathogenesis has been limited. Angiopoietin-like 4 (ANGPTL4) is a protein secreted in response to hypoxic and nutrient-poor conditions...

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Main Authors: Pavan K. Bhatraju, MD, MSc, Eric D. Morrell, MD, Ian B. Stanaway, PhD, Neha A. Sathe, MD, MSc, Avantika Srivastava, MS, Radu Postelnicu, MD, Richard Green, BS, Adair Andrews, BSN, Martin Gonzalez, BS, Christopher J. Kratochvil, MD, Vishakha K. Kumar, BS, Tien-Ying Hsiang, PhD, Michael Gale, Jr, PhD, George L. Anesi, MD, David Wyles, MD, M. Jana Broadhurst, MD, PhD, David Brett-Major, MD, MPH, Vikramjit Mukherjee, MD, Jonathan E. Sevransky, MD, Douglas Landsittel, PhD, Chi Hung, MD, William A. Altemeier, MD, Sina A. Gharib, MD, Timothy M. Uyeki, MD, MPH, J. Perren Cobb, MD, Janice M. Liebler, MD, David R. Crosslin, PhD, Gail P. Jarvik, MD, Leopoldo N. Segal, MD, Laura Evans, MD, Carmen Mikacenic, MD, Mark M. Wurfel, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2023-01-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000827

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http://journals.lww.com/10.1097/CCE.0000000000000827

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